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Heme oxygenase-1 inducer and carbon monoxide–releasing molecule enhance the effects of gabapentinoids by modulating glial activation during neuropathic pain in mice
INTRODUCTION: Neuropathic pain is one of the most difficult-to-treat symptoms. Although gabapentinoids are classified as first-line drugs, they have only modest efficacy. OBJECTIVES: The aim of this study was to investigate whether treatment with the heme oxygenase-1 (HO-1) inducer cobalt protoporph...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181470/ https://www.ncbi.nlm.nih.gov/pubmed/30534628 http://dx.doi.org/10.1097/PR9.0000000000000677 |