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Induction of human somatostatin and parvalbumin neurons by expressing a single transcription factor LIM homeobox 6

Human GABAergic interneurons (GIN) are implicated in normal brain function and in numerous mental disorders. However, the generation of functional human GIN subtypes from human pluripotent stem cells (hPSCs) has not been established. By expressing LHX6, a transcriptional factor that is critical for...

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Detalles Bibliográficos
Autores principales: Yuan, Fang, Chen, Xin, Fang, Kai-Heng, Wang, Yuanyuan, Lin, Mingyan, Xu, Shi-Bo, Huo, Hai-Qin, Xu, Min, Ma, Lixiang, Chen, Yuejun, He, Shuijin, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181563/
https://www.ncbi.nlm.nih.gov/pubmed/30251953
http://dx.doi.org/10.7554/eLife.37382