Prolonged activation of cAMP signaling leads to endothelial barrier disruption via transcriptional repression of RRAS

The increase in cAMP levels in endothelial cells triggers cellular signaling to alter vascular permeability. It is generally considered that cAMP signaling stabilizes the endothelial barrier function and reduces permeability. However, previous studies have only examined the permeability shortly afte...

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Detalles Bibliográficos
Autores principales: Perrot, Carole Y., Sawada, Junko, Komatsu, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181640/
https://www.ncbi.nlm.nih.gov/pubmed/29775418
http://dx.doi.org/10.1096/fj.201700818RRR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181640/
https://www.ncbi.nlm.nih.gov/pubmed/29775418
http://dx.doi.org/10.1096/fj.201700818RRR

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