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Prolonged activation of cAMP signaling leads to endothelial barrier disruption via transcriptional repression of RRAS
The increase in cAMP levels in endothelial cells triggers cellular signaling to alter vascular permeability. It is generally considered that cAMP signaling stabilizes the endothelial barrier function and reduces permeability. However, previous studies have only examined the permeability shortly afte...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Federation of American Societies for Experimental Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181640/ https://www.ncbi.nlm.nih.gov/pubmed/29775418 http://dx.doi.org/10.1096/fj.201700818RRR |