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PAR-1 is a novel mechano-sensor transducing laminar flow-mediated endothelial signaling

Recent studies have indicated that protease-activated receptor-1 (PAR-1) is involved in cytoprotective and anti-inflammatory responses in endothelial cells (ECs). However, the role of PAR-1 in laminar flow-mediated atheroprotective responses remains unknown. Herein, we investigated whether PAR-1 reg...

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Detalles Bibliográficos
Autores principales: Kim, Suji, Han, Jung-Hwa, Nam, Dae-Hwan, Kim, Geun-Young, Lim, Jae Hyang, Kim, Jae-Ryong, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181929/
https://www.ncbi.nlm.nih.gov/pubmed/30310081
http://dx.doi.org/10.1038/s41598-018-33222-3