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Exosomes from normal and diabetic human corneolimbal keratocytes differentially regulate migration, proliferation and marker expression of limbal epithelial cells

Limbal epithelial stem cells (LESC) maintenance requires communication between stem cells and neighboring stromal keratocytes. Extracellular vesicles (EVs) are important for intercellular communication in various stem cell niches. We explored the regulatory roles of limbal stromal cell (LSC)-derived...

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Detalles Bibliográficos
Autores principales: Leszczynska, Aleksandra, Kulkarni, Mangesh, Ljubimov, Alexander V., Saghizadeh, Mehrnoosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182003/
https://www.ncbi.nlm.nih.gov/pubmed/30310159
http://dx.doi.org/10.1038/s41598-018-33169-5