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CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii

Toxoplasma gondii, an Apicomplexan parasite, causes significant morbidity and mortality, including severe disease in immunocompromised hosts and devastating congenital disease, with no effective treatment for the bradyzoite stage. To address this, we used the Tropical Disease Research database, crys...

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Detalles Bibliográficos
Autores principales: Lykins, Joseph D., Filippova, Ekaterina V., Halavaty, Andrei S., Minasov, George, Zhou, Ying, Dubrovska, Ievgeniia, Flores, Kristin J., Shuvalova, Ludmilla A., Ruan, Jiapeng, El Bissati, Kamal, Dovgin, Sarah, Roberts, Craig W., Woods, Stuart, Moulton, Jon D., Moulton, Hong, McPhillie, Martin J., Muench, Stephen P., Fishwick, Colin W. G., Sabini, Elisabetta, Shanmugam, Dhanasekaran, Roos, David S., McLeod, Rima, Anderson, Wayne F., Ngô, Huân M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182094/
https://www.ncbi.nlm.nih.gov/pubmed/30345257
http://dx.doi.org/10.3389/fcimb.2018.00352