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Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule

The elimination of smallpox as an endemic disease and the obvious ethical problems with clinical challenge requires the efficacy evaluation of medical countermeasures against smallpox using the FDA Animal Rule. This approach requires the evaluation of antiviral efficacy in an animal model whose infe...

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Detalles Bibliográficos
Autores principales: Perry, Mark R., Warren, Richard, Merchlinsky, Michael, Houchens, Christopher, Rogers, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182097/
https://www.ncbi.nlm.nih.gov/pubmed/30345258
http://dx.doi.org/10.3389/fcimb.2018.00356