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The Role of the Immunological Synapse in Differential Effects of APC Subsets in Alloimmunization to Fresh, Non-stored RBCs

Background: Each year, over 5 million red blood cell (RBC) transfusions are administered to patients in the USA. Despite the therapeutic benefits of RBC transfusions, there are associated risks. RBC-specific alloantibodies may form in response to antigenic differences between RBC donors and recipien...

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Detalles Bibliográficos
Autores principales: Richards, Amanda L., Sheldon, Kathryn, Wu, Xiaoping, Gruber, David R., Hudson, Krystalyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182098/
https://www.ncbi.nlm.nih.gov/pubmed/30344520
http://dx.doi.org/10.3389/fimmu.2018.02200