Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features

The structure-specific ERCC1-XPF endonuclease plays a key role in DNA damage excision by nucleotide excision repair (NER) and interstrand crosslink repair. Mutations in this complex can either cause xeroderma pigmentosum (XP) or XP combined with Cockayne syndrome (XPCS-complex) or Fanconi anemia. Ho...

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Detalles Bibliográficos
Autores principales: Sabatella, Mariangela, Theil, Arjan F, Ribeiro-Silva, Cristina, Slyskova, Jana, Thijssen, Karen, Voskamp, Chantal, Lans, Hannes, Vermeulen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182131/
https://www.ncbi.nlm.nih.gov/pubmed/30165384
http://dx.doi.org/10.1093/nar/gky774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182131/
https://www.ncbi.nlm.nih.gov/pubmed/30165384
http://dx.doi.org/10.1093/nar/gky774

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