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Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features
The structure-specific ERCC1-XPF endonuclease plays a key role in DNA damage excision by nucleotide excision repair (NER) and interstrand crosslink repair. Mutations in this complex can either cause xeroderma pigmentosum (XP) or XP combined with Cockayne syndrome (XPCS-complex) or Fanconi anemia. Ho...
Autores principales: | Sabatella, Mariangela, Theil, Arjan F, Ribeiro-Silva, Cristina, Slyskova, Jana, Thijssen, Karen, Voskamp, Chantal, Lans, Hannes, Vermeulen, Wim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182131/ https://www.ncbi.nlm.nih.gov/pubmed/30165384 http://dx.doi.org/10.1093/nar/gky774 |
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