Exploiting CRISPR–Cas9 technology to investigate individual histone modifications

Despite their importance for most DNA-templated processes, the function of individual histone modifications has remained largely unknown because in vivo mutational analyses are lacking. The reason for this is that histone genes are encoded by multigene families and that tools to simultaneously edit...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasquez, Juan-José, Wedel, Carolin, Cosentino, Raul O, Siegel, T Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182134/
https://www.ncbi.nlm.nih.gov/pubmed/29912461
http://dx.doi.org/10.1093/nar/gky517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182134/
https://www.ncbi.nlm.nih.gov/pubmed/29912461
http://dx.doi.org/10.1093/nar/gky517

Ejemplares similares