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Exploiting CRISPR–Cas9 technology to investigate individual histone modifications
Despite their importance for most DNA-templated processes, the function of individual histone modifications has remained largely unknown because in vivo mutational analyses are lacking. The reason for this is that histone genes are encoded by multigene families and that tools to simultaneously edit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182134/ https://www.ncbi.nlm.nih.gov/pubmed/29912461 http://dx.doi.org/10.1093/nar/gky517 |