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Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex

Diversity-generating retroelements (DGRs) create unparalleled levels of protein sequence variation through mutagenic retrohoming. Sequence information is transferred from an invariant template region (TR), through an RNA intermediate, to a protein-coding variable region. Selective infidelity at aden...

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Detalles Bibliográficos
Autores principales: Handa, Sumit, Jiang, Yong, Tao, Sijia, Foreman, Robert, Schinazi, Raymond F, Miller, Jeff F, Ghosh, Partho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182149/
https://www.ncbi.nlm.nih.gov/pubmed/30007279
http://dx.doi.org/10.1093/nar/gky620