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Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex
Diversity-generating retroelements (DGRs) create unparalleled levels of protein sequence variation through mutagenic retrohoming. Sequence information is transferred from an invariant template region (TR), through an RNA intermediate, to a protein-coding variable region. Selective infidelity at aden...
Autores principales: | Handa, Sumit, Jiang, Yong, Tao, Sijia, Foreman, Robert, Schinazi, Raymond F, Miller, Jeff F, Ghosh, Partho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182149/ https://www.ncbi.nlm.nih.gov/pubmed/30007279 http://dx.doi.org/10.1093/nar/gky620 |
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