Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage

Sensitivity and resistance of cells to platinum drug chemotherapy are to a large extent determined by activity of the DNA damage response (DDR). Combining chemotherapy with inhibition of specific DDR pathways could therefore improve treatment efficacy. Multiple DDR pathways have been implicated in r...

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Detalles Bibliográficos
Autores principales: Slyskova, Jana, Sabatella, Mariangela, Ribeiro-Silva, Cristina, Stok, Colin, Theil, Arjan F, Vermeulen, Wim, Lans, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182164/
https://www.ncbi.nlm.nih.gov/pubmed/30137419
http://dx.doi.org/10.1093/nar/gky764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182164/
https://www.ncbi.nlm.nih.gov/pubmed/30137419
http://dx.doi.org/10.1093/nar/gky764

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