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A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme

Adenosine deaminases that act on RNA (ADARs) convert adenosine to inosine within double-stranded regions of RNA, resulting in increased transcriptomic diversity, as well as protection of cellular double-stranded RNA (dsRNA) from silencing and improper immune activation. The presence of dsRNA-binding...

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Detalles Bibliográficos
Autores principales: Rajendren, Suba, Manning, Aidan C, Al-Awadi, Haider, Yamada, Kentaro, Takagi, Yuichiro, Hundley, Heather A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182170/
https://www.ncbi.nlm.nih.gov/pubmed/30202880
http://dx.doi.org/10.1093/nar/gky800