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A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme
Adenosine deaminases that act on RNA (ADARs) convert adenosine to inosine within double-stranded regions of RNA, resulting in increased transcriptomic diversity, as well as protection of cellular double-stranded RNA (dsRNA) from silencing and improper immune activation. The presence of dsRNA-binding...
Autores principales: | Rajendren, Suba, Manning, Aidan C, Al-Awadi, Haider, Yamada, Kentaro, Takagi, Yuichiro, Hundley, Heather A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182170/ https://www.ncbi.nlm.nih.gov/pubmed/30202880 http://dx.doi.org/10.1093/nar/gky800 |
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