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Independent erosion of conserved transcription factor binding sites points to shared hindlimb, vision and external testes loss in different mammals

Genetic variation in cis-regulatory elements is thought to be a major driving force in morphological and physiological changes. However, identifying transcription factor binding events that code for complex traits remains a challenge, motivating novel means of detecting putatively important binding...

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Detalles Bibliográficos
Autores principales: Berger, Mark J, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182171/
https://www.ncbi.nlm.nih.gov/pubmed/30137416
http://dx.doi.org/10.1093/nar/gky741