The ATPase activity of E. coli RecA prevents accumulation of toxic complexes formed by erroneous binding to undamaged double stranded DNA

The Escherichia coli RecA protein catalyzes the central step of homologous recombination using its homology search and strand exchange activity. RecA is a DNA-dependent ATPase, but its homology search and strand exchange activities are largely independent of its ATPase activity. ATP hydrolysis conve...

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Detalles Bibliográficos
Autores principales: Gataulin, Daniil V, Carey, Jeffrey N, Li, Junya, Shah, Parisha, Grubb, Jennifer T, Bishop, Douglas K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182174/
https://www.ncbi.nlm.nih.gov/pubmed/30137528
http://dx.doi.org/10.1093/nar/gky748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182174/
https://www.ncbi.nlm.nih.gov/pubmed/30137528
http://dx.doi.org/10.1093/nar/gky748

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