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OPTHiS Identifies the Molecular Basis of the Direct Interaction between CSL and SMRT Corepressor
Notch signaling is an evolutionarily conserved pathway and involves in the regulation of various cellular and developmental processes. Ligand binding releases the intracellular domain of Notch receptor (NICD), which interacts with DNA-bound CSL [CBF1/Su(H)/Lag-1] to activate transcription of target...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182220/ https://www.ncbi.nlm.nih.gov/pubmed/30157580 http://dx.doi.org/10.14348/molcells.2018.0196 |