Cargando…

OPTHiS Identifies the Molecular Basis of the Direct Interaction between CSL and SMRT Corepressor

Notch signaling is an evolutionarily conserved pathway and involves in the regulation of various cellular and developmental processes. Ligand binding releases the intracellular domain of Notch receptor (NICD), which interacts with DNA-bound CSL [CBF1/Su(H)/Lag-1] to activate transcription of target...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Gwang Sik, Park, Hee-Sae, Lee, Young Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182220/
https://www.ncbi.nlm.nih.gov/pubmed/30157580
http://dx.doi.org/10.14348/molcells.2018.0196