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Interactions of Mexiletine with Novel Antiepileptic Drugs in the Maximal Electroshock Test in Mice: An Isobolographic Analysis

The aim of the study was to evaluate precisely the type of interactions between mexiletine (an antiarrhythmic drug) and four new generation antiepileptic drugs: lamotrigine, oxcarbazepine, topiramate and pregabalin in the maximal electroshock test in mice (MES). The isobolographic analysis was used...

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Detalles Bibliográficos
Autores principales: Wróblewska, Dorota, Rudkowska, Monika, Banach, Monika, Borowicz-Reutt, Kinga K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182375/
https://www.ncbi.nlm.nih.gov/pubmed/30117096
http://dx.doi.org/10.1007/s11064-018-2606-8