Population Pharmacokinetics and Exposure-Response Relationships of Naldemedine

PURPOSE: To characterize population pharmacokinetic (PK) of naldemedine, to identify factors which influence naldemedine PK, and to evaluate their clinical relevancy based on exposure-response relationships. METHODS: A population PK model was developed with pooled naldemedine concentrations from hea...

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Detalles Bibliográficos
Autores principales: Kubota, Ryuji, Fukumura, Kazuya, Wajima, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182381/
https://www.ncbi.nlm.nih.gov/pubmed/30280262
http://dx.doi.org/10.1007/s11095-018-2501-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182381/
https://www.ncbi.nlm.nih.gov/pubmed/30280262
http://dx.doi.org/10.1007/s11095-018-2501-7

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