Pharmacokinetics, Pharmacodynamics, and Safety of the Novel Calcimimetic Agent Evocalcet in Healthy Japanese Subjects: First-in-Human Phase I Study

BACKGROUND AND OBJECTIVES: Evocalcet is a novel calcimimetic agent with potential to improve the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. This study aimed to determine the pharmacokinetics, pharmacodynamics, and safety of evocalcet in healthy Japanese subje...

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Detalles Bibliográficos
Autores principales: Akizawa, Tadao, Shimazaki, Ryutaro, Shiramoto, Masanari, Fukagawa, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182462/
https://www.ncbi.nlm.nih.gov/pubmed/30168004
http://dx.doi.org/10.1007/s40261-018-0687-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182462/
https://www.ncbi.nlm.nih.gov/pubmed/30168004
http://dx.doi.org/10.1007/s40261-018-0687-4

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