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Diastereoselective C–H carbonylative annulation of aliphatic amines: a rapid route to functionalized γ-lactams
A palladium(ii)-catalysed C(sp(3))–H carbonylation of free(NH) secondary aliphatic amines to 2-pyrrolidinones is described. A correlation between the nature of the carboxylate ligand and the diastereoselectivity and yield of the process was observed. As such, under these optimal conditions a range o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182607/ https://www.ncbi.nlm.nih.gov/pubmed/30393523 http://dx.doi.org/10.1039/c8sc02855a |