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Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes

AIMS/HYPOTHESIS: The study aimed to determine whether discrete subtypes of type 1 diabetes exist, based on immunoregulatory profiles at clinical onset, as this has significant implications for disease treatment and prevention as well as the design and analysis of clinical trials. METHODS: Using a pl...

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Detalles Bibliográficos
Autores principales: Cabrera, Susanne M., Engle, Samuel, Kaldunski, Mary, Jia, Shuang, Geoffrey, Rhonda, Simpson, Pippa, Szabo, Aniko, Speake, Cate, Greenbaum, Carla J., Chen, Yi-Guang, Hessner, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182660/
https://www.ncbi.nlm.nih.gov/pubmed/30167736
http://dx.doi.org/10.1007/s00125-018-4708-x