Affinities of human NMDA receptor autoantibodies: implications for disease mechanisms and clinical diagnostics

Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a common autoimmune encephalitis presenting with psychosis, dyskinesias, autonomic dysfunction and seizures. The underlying autoantibodies against the NR1 subunit are directly pathogenic by disrupting synaptic NMDAR currents. However, antibo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ly, Lam-Thanh, Kreye, Jakob, Jurek, Betty, Leubner, Jonas, Scheibe, Franziska, Lemcke, Johannes, Wenke, Nina Kerstin, Reincke, Sebastian Momsen, Prüss, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182686/
https://www.ncbi.nlm.nih.gov/pubmed/30187160
http://dx.doi.org/10.1007/s00415-018-9042-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182686/
https://www.ncbi.nlm.nih.gov/pubmed/30187160
http://dx.doi.org/10.1007/s00415-018-9042-1

Ejemplares similares