Chitosan/hyaluronic acid/plasmid-DNA nanoparticles encoding interleukin-1 receptor antagonist attenuate inflammation in synoviocytes induced by interleukin-1 beta

Synovial inflammation mainly resulting from interleukin-1 beta (IL-1β) plays a crucial role in the early and late stage of osteoarthritis. Recent progress in therapeutic gene delivery systems has led to promising strategies for local sustained target gene expression. The aim of this study was to des...

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Detalles Bibliográficos
Autores principales: Deng, Rong-Hui, Qiu, Bo, Zhou, Pang-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Biocompatibility Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182723/
https://www.ncbi.nlm.nih.gov/pubmed/30276528
http://dx.doi.org/10.1007/s10856-018-6160-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182723/
https://www.ncbi.nlm.nih.gov/pubmed/30276528
http://dx.doi.org/10.1007/s10856-018-6160-3

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