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Phase Ib study of irinotecan and ramucirumab for advanced gastric cancer previously treated with fluoropyrimidine with/without platinum and taxane

PURPOSE: Optimal salvage chemotherapy for patients with treated advanced/metastatic gastric cancer (AGC) is unknown. Irinotecan is commonly used in Japan. Ramucirumab, a human IgG-1 monoclonal antibody targeting the extracellular domain of VEGF receptor 2, is the first molecularly targeted agent pro...

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Detalles Bibliográficos
Autores principales: Satake, Hironaga, Sagawa, Tamotsu, Fujikawa, Koshi, Hatachi, Yukimasa, Yasui, Hisateru, Kotaka, Masahito, Kato, Takeshi, Tsuji, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182742/
https://www.ncbi.nlm.nih.gov/pubmed/30167847
http://dx.doi.org/10.1007/s00280-018-3678-5