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Phase Ib study of irinotecan and ramucirumab for advanced gastric cancer previously treated with fluoropyrimidine with/without platinum and taxane
PURPOSE: Optimal salvage chemotherapy for patients with treated advanced/metastatic gastric cancer (AGC) is unknown. Irinotecan is commonly used in Japan. Ramucirumab, a human IgG-1 monoclonal antibody targeting the extracellular domain of VEGF receptor 2, is the first molecularly targeted agent pro...
Autores principales: | Satake, Hironaga, Sagawa, Tamotsu, Fujikawa, Koshi, Hatachi, Yukimasa, Yasui, Hisateru, Kotaka, Masahito, Kato, Takeshi, Tsuji, Akihito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182742/ https://www.ncbi.nlm.nih.gov/pubmed/30167847 http://dx.doi.org/10.1007/s00280-018-3678-5 |
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