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An improved secretion signal enhances the secretion of model proteins from Pichia pastoris

BACKGROUND: Proteins can be secreted from a host organism with the aid of N-terminal secretion signals. The budding yeast Pichia pastoris (Komagataella sp.) is widely employed to secrete proteins of academic and industrial interest. For this yeast, the most commonly used secretion signal is the N-te...

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Detalles Bibliográficos
Autores principales: Barrero, Juan J., Casler, Jason C., Valero, Francisco, Ferrer, Pau, Glick, Benjamin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182871/
https://www.ncbi.nlm.nih.gov/pubmed/30314480
http://dx.doi.org/10.1186/s12934-018-1009-5