siAbasic: a comprehensive database for potent siRNA-6Ø sequences without off-target effects

Small interfering RNA (siRNA) is widely used to specifically silence target gene expression, but its microRNA (miRNA)-like function inevitably suppresses hundreds of off-targets. Recently, complete elimination of the off-target repression has been achieved by introducing an abasic nucleotide to the...

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Detalles Bibliográficos
Autores principales: Park, Jongyeun, Ahn, Seung Hyun, Cho, Kwang Moon, Gu, Dowoon, Jang, Eun-Sook, Chi, Sung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183071/
https://www.ncbi.nlm.nih.gov/pubmed/30321353
http://dx.doi.org/10.1093/database/bay109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183071/
https://www.ncbi.nlm.nih.gov/pubmed/30321353
http://dx.doi.org/10.1093/database/bay109

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