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Safety, tolerability and immunogenicity of the ExPEC4V (JNJ-63871860) vaccine for prevention of invasive extraintestinal pathogenic Escherichia coli disease: A phase 1, randomized, double-blind, placebo-controlled study in healthy Japanese participants

This Phase 1, randomized, double-blind, placebo-controlled study was conducted to evaluate the safety, tolerability and immunogenicity of different doses of ExPEC4V conjugate vaccine (4-16µg Polysaccharide [PS]/serotype) in healthy Japanese participants, stratified into younger (≥20 to <50 years)...

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Detalles Bibliográficos
Autores principales: Inoue, Megumi, Ogawa, Tetsuro, Tamura, Hiroshi, Hagiwara, Yosuke, Saito, Yuki, Abbanat, Darren, van den Dobbelsteen, Germie, Hermans, Peter, Thoelen, Stefan, Poolman, Jan, Ibarra de Palacios, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183137/
https://www.ncbi.nlm.nih.gov/pubmed/29771596
http://dx.doi.org/10.1080/21645515.2018.1474316