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More robust gut immune responses induced by combining intranasal and sublingual routes for prime-boost immunization

Norovirus causes acute and debilitating gastroenteritis, characterized by vomiting and diarrhea. We recently reported a recombinant GII. 4 P domain particle (Pd) vaccine adjuvanted with a flagellin, Vibrio vulnificus FlaB, effectively promoting both humoral and cell-mediated immune responses. In the...

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Detalles Bibliográficos
Autores principales: Hwang, Hye Suk, Puth, Sao, Tan, Wenzhi, Verma, Vivek, Jeong, Kwangjoon, Lee, Shee Eun, Rhee, Joon Haeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183199/
https://www.ncbi.nlm.nih.gov/pubmed/29781755
http://dx.doi.org/10.1080/21645515.2018.1472185