Rational design of heat stable lyophilized rotavirus vaccine formulations

To develop a safe and efficacious heat-stable rotavirus vaccine, new lyophilized formulations were developed using rotavirus serotypes constituting RotaTeq®. A series of formulation compositions, differing in buffering agents, bulking agents, cryoprotectants, amino acids and divalent cations, were s...

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Detalles Bibliográficos
Autores principales: Madan, Madhu, Sikriwal, Deepa, Sharma, Gaurav, Shukla, Nidhi, Mandyal, Ashwani Kumar, Kale, Sachin, Gill, Davinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183320/
https://www.ncbi.nlm.nih.gov/pubmed/29953317
http://dx.doi.org/10.1080/21645515.2018.1487499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183320/
https://www.ncbi.nlm.nih.gov/pubmed/29953317
http://dx.doi.org/10.1080/21645515.2018.1487499

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