Cargando…

Complex formation between platelet-derived growth factor receptor β and transforming growth factor β receptor regulates the differentiation of mesenchymal stem cells into cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs) have recently gained attention as potent targets in cancer therapy because they are a crucial component of the tumor microenvironment and promote the growth and invasion of cancer cells. CAFs differentiate from fibroblasts, mesenchymal stem cells (MSCs), epitheli...

Descripción completa

Detalles Bibliográficos
Autores principales: Aoto, Kaori, Ito, Kousei, Aoki, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183337/
https://www.ncbi.nlm.nih.gov/pubmed/30344924
http://dx.doi.org/10.18632/oncotarget.26124