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Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity

Adoptive T-cell therapy with T cell receptor (TCR) -engineered T cells is an attractive strategy for cancer treatment and the success in this therapy is dependent on the functional avidity of the transduced TCRs against targeted tumor antigens. Therefore, the establishment of the methodology of the...

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Detalles Bibliográficos
Autores principales: Morimoto, Soyoko, Fujiki, Fumihiro, Kondo, Kenta, Nakajima, Hiroko, Kobayashi, Yoshiki, Inatome, Miki, Aoyama, Nao, Nishida, Yuya, Tsuboi, Akihiro, Oka, Yoshihiro, Nishida, Sumiyuki, Nakata, Jun, Hosen, Naoki, Oji, Yusuke, Sugiyama, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183340/
https://www.ncbi.nlm.nih.gov/pubmed/30344927
http://dx.doi.org/10.18632/oncotarget.26139