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Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis

Phospholipids regulate numerous cellular functions and their deregulation is known to be associated with cancer development. Here, we show for the first time that expression of the E6 oncoprotein of human papillomavirus type 8 (HPV8) leads to a profound increase in nuclear phosphatidylinositol-4,5-b...

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Detalles Bibliográficos
Autores principales: Marx, Benjamin, Hufbauer, Martin, Zigrino, Paola, Majewski, Slawomir, Markiefka, Birgid, Sachsenheimer, Timo, Brügger, Britta, Akgül, Baki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183346/
https://www.ncbi.nlm.nih.gov/pubmed/30344928
http://dx.doi.org/10.18632/oncotarget.26140