Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway

BACKGROUND: NUDT21 is a mammalian precursor mRNA(pre-mRNA) 3’ end processing factor and plays an important role in the selection of poly(A) sites in 3’-untranslated region (3’-UTR). NUDT21 links alternative polyadenylation with regulation of glioblastoma and osteosarcoma progression and is found to...

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Detalles Bibliográficos
Autores principales: Zhang, Lan, Zhang, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183658/
https://www.ncbi.nlm.nih.gov/pubmed/30349365
http://dx.doi.org/10.2147/CMAR.S173496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183658/
https://www.ncbi.nlm.nih.gov/pubmed/30349365
http://dx.doi.org/10.2147/CMAR.S173496

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