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Knockdown of NUDT21 inhibits proliferation and promotes apoptosis of human K562 leukemia cells through ERK pathway
BACKGROUND: NUDT21 is a mammalian precursor mRNA(pre-mRNA) 3’ end processing factor and plays an important role in the selection of poly(A) sites in 3’-untranslated region (3’-UTR). NUDT21 links alternative polyadenylation with regulation of glioblastoma and osteosarcoma progression and is found to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183658/ https://www.ncbi.nlm.nih.gov/pubmed/30349365 http://dx.doi.org/10.2147/CMAR.S173496 |