Rif1 inhibits replication fork progression and controls DNA copy number in Drosophila

Control of DNA copy number is essential to maintain genome stability and ensure proper cell and tissue function. In Drosophila polyploid cells, the SNF2-domain-containing SUUR protein inhibits replication fork progression within specific regions of the genome to promote DNA underreplication. While d...

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Detalles Bibliográficos
Autores principales: Munden, Alexander, Rong, Zhan, Sun, Amanda, Gangula, Rama, Mallal, Simon, Nordman, Jared T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185109/
https://www.ncbi.nlm.nih.gov/pubmed/30277458
http://dx.doi.org/10.7554/eLife.39140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185109/
https://www.ncbi.nlm.nih.gov/pubmed/30277458
http://dx.doi.org/10.7554/eLife.39140

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