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Turning Vice into Virtue: Using Batch-Effects to Detect Errors in Large Genomic Data Sets

It is often unavoidable to combine data from different sequencing centers or sequencing platforms when compiling data sets with a large number of individuals. However, the different data are likely to contain specific systematic errors that will appear as SNPs. Here, we devise a method to detect sys...

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Detalles Bibliográficos
Autores principales: Mafessoni, Fabrizio, Prasad, Rashmi B, Groop, Leif, Hansson, Ola, Prüfer, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185451/
https://www.ncbi.nlm.nih.gov/pubmed/30204860
http://dx.doi.org/10.1093/gbe/evy199