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In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein
Methotrexate (MTX) is a widely used chemotherapeutic agent, immune suppressant and antimalarial drug. It is a substrate of several human ABC proteins that confer multidrug resistance to cancer cells and determine compartmentalization of a wide range of physiological metabolites and endo or xenobioti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185855/ https://www.ncbi.nlm.nih.gov/pubmed/30312334 http://dx.doi.org/10.1371/journal.pone.0205657 |