Functional recovery after dantrolene-supplementation of cold stored hearts using an ex vivo isolated working rat heart model

The ryanodine receptor antagonist dantrolene inhibits calcium release from the sarcoplasmic reticulum and reduces cardiac ischaemia-reperfusion injury (IRI) in global warm ischaemia models however the cardioprotective potential of dantrolene under hypothermic conditions is unknown. This study addres...

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Detalles Bibliográficos
Autores principales: Villanueva, Jeanette E., Gao, Ling, Chew, Hong C., Hicks, Mark, Doyle, Aoife, Qui, Min Ru, Dhital, Kumud K., Macdonald, Peter S., Jabbour, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185861/
https://www.ncbi.nlm.nih.gov/pubmed/30312353
http://dx.doi.org/10.1371/journal.pone.0205850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185861/
https://www.ncbi.nlm.nih.gov/pubmed/30312353
http://dx.doi.org/10.1371/journal.pone.0205850

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