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A dimeric fluorescent protein yields a bright, red-shifted GEVI capable of population signals in brain slice

A bright, red-shifted Genetically Encoded Voltage Indicator (GEVI) was developed using a modified version of the fluorescent protein, tdTomato. Dimerization of the fluorescent domain for ArcLight-type GEVIs has been shown to affect the signal size of the voltage-dependent optical signal. For red-shi...

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Detalles Bibliográficos
Autores principales: Yi, Bumjun, Kang, Bok Eum, Lee, Sungmoo, Braubach, Sophie, Baker, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185910/
https://www.ncbi.nlm.nih.gov/pubmed/30315245
http://dx.doi.org/10.1038/s41598-018-33297-y