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A dimeric fluorescent protein yields a bright, red-shifted GEVI capable of population signals in brain slice
A bright, red-shifted Genetically Encoded Voltage Indicator (GEVI) was developed using a modified version of the fluorescent protein, tdTomato. Dimerization of the fluorescent domain for ArcLight-type GEVIs has been shown to affect the signal size of the voltage-dependent optical signal. For red-shi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185910/ https://www.ncbi.nlm.nih.gov/pubmed/30315245 http://dx.doi.org/10.1038/s41598-018-33297-y |