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DUSP10 constrains innate IL-33-mediated cytokine production in ST2(hi) memory-type pathogenic Th2 cells
ST2(hi) memory-type Th2 cells are identified as a pathogenic subpopulation in eosinophilic airway inflammation. These ST2(hi) pathogenic Th2 cells produce large amount of IL-5 upon T cell receptor stimulation, but not in response to IL-33 treatment. By contrast, IL-33 alone induces cytokine producti...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185962/ https://www.ncbi.nlm.nih.gov/pubmed/30315197 http://dx.doi.org/10.1038/s41467-018-06468-8 |