Cargando…

Selective DNAM-1 expression on small peritoneal macrophages contributes to CD4(+) T cell costimulation

Mouse peritoneal macrophages consist of two subsets: large peritoneal macrophages (LPMs) and small peritoneal macrophages (SPMs), defined as CD11b(hi)F4/80(hi) and CD11b(+)F4/80(lo) cells, respectively. We reveal that SPMs, but not LPMs, have the ability to present antigens to naïve CD4(+) T cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Takenaka, Eri, Van Vo, Anh, Yamashita-Kanemaru, Yumi, Shibuya, Akira, Shibuya, Kazuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185969/
https://www.ncbi.nlm.nih.gov/pubmed/30315271
http://dx.doi.org/10.1038/s41598-018-33437-4