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Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis

Intestinal fibrosis is thought to be a consequence of excessive tissue repair, and constitutes a common problem in patients with Crohn’s disease (CD). While fibrosis seems to require inflammation as a prerequisite it is unclear whether the severity or persistence of inflammation influences the degre...

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Detalles Bibliográficos
Autores principales: Hünerwadel, A., Fagagnini, S., Rogler, G., Lutz, C., Jaeger, S. U., Mamie, C., Weder, B., Ruiz, P. A., Hausmann, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185984/
https://www.ncbi.nlm.nih.gov/pubmed/30315190
http://dx.doi.org/10.1038/s41598-018-33452-5