Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset

OBJECTIVE: We aimed to assess whether differences in energy metabolism in fibroblast cell lines derived from patients with Huntington disease were associated with age at onset independent of the cytosine-adenine-guanine (CAG) repeat number in the mutant allele. METHODS: For this study, we selected 9...

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Detalles Bibliográficos
Autores principales: Gardiner, Sarah L., Milanese, Chiara, Boogaard, Merel W., Buijsen, Ronald A.M., Hogenboom, Marye, Roos, Raymund A.C., Mastroberardino, Pier G., van Roon-Mom, Willeke M.C., Aziz, N. Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186024/
https://www.ncbi.nlm.nih.gov/pubmed/30338295
http://dx.doi.org/10.1212/NXG.0000000000000275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186024/
https://www.ncbi.nlm.nih.gov/pubmed/30338295
http://dx.doi.org/10.1212/NXG.0000000000000275

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