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Identification of a novel MTAP-RAF1 fusion in a soft tissue sarcoma

BACKGROUND: RAF family activating fusions have been described as a potentially targetable molecular finding in a subset of soft tissue sarcomas. To further expand upon the landscape of this genetic feature, we describe a novel MTAP-RAF1 activating fusion identified in a S100 positive soft tissue sar...

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Detalles Bibliográficos
Autores principales: Hicks, J. Kevin, Henderson-Jackson, Evita, Duggan, Julia, Joyce, David M., Brohl, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186031/
https://www.ncbi.nlm.nih.gov/pubmed/30314519
http://dx.doi.org/10.1186/s13000-018-0759-z